January 05, 2012
NIMH Pages about Clinical Research and Trials
Overview of Clinical Research and Trials…
Publications about Clinical Research and Trials
- Neuroimaging and Mental Illness: A Window Into the Brain
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Researchers use brain scans to study brain development in healthy people and people with illnesses. This publication answers frequently asked questions about what brain scans can and cannot do related to diagnosing mental illnesses.
- A Participant's Guide to Mental Health Clinical Research
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This brochure, prepared by the National Institute of Mental Health (NIMH), provides answers to common questions about volunteering for mental health clinical research.
Science News about Clinical Research and Trials
- Atypical Antipsychotic More Effective than Older Drugs in Treating Childhood Mania, but Side Effects Can Be Serious
- Science Update • January 11, 2012
The antipsychotic medication risperidone is more effective for initial treatment of mania in children diagnosed with bipolar disorder compared to other mood stabilizing medications, but it carries the potential for serious metabolic side effects, according to an NIMH-funded study published online ahead of print January 2, 2012, in the Archives of General Psychiatry. - Suspect Gene Variants Boost PTSD Risk after Mass Shooting
- Science Update • December 01, 2011
College students exposed to a mass shooting were 20-30 percent more likely to later develop post traumatic stress disorder (PTSD) symptoms if they harbored a risk version of a gene, NIMH-funded researchers have discovered. - Interventions Show Promise in Treating Depression Among Preschoolers
- Science Update • November 17, 2011
A new psychosocial approach shows promise in helping preschoolers with symptoms of depression function better and learn to regulate their emotions, according to an NIMH-funded study published online ahead of print October 31, 2011, in the Journal of Child Psychology and Psychiatry. - Our Brains Are Made of the Same Stuff, Despite DNA Differences
- Press Release • October 26, 2011
Despite vast differences in the genetic code across individuals and ethnicities, the human brain shows a “consistent molecular architecture.” The finding is from a pair of studies that have created databases revealing when and where genes turn on and off in multiple brain regions through development. - Continued Use of Stimulants for ADHD Likely Does Not Increase Risk for Hypertension, but May Affect Heart Rate
- Science Update • September 07, 2011
Chronic use of stimulant medication to treat attention deficit hyperactivity disorder (ADHD) in children does not appear to increase risk for high blood pressure over the long term, but it may have modest effects on heart rate, according to follow-up data from the NIMH-funded Multimodal Treatment Study of Children with ADHD (MTA).
More Science News about Clinical Research and Trials
Posts about Clinical Research and Trials
December 23, 2011
NIMH’s Top 10 Research Advances of 2011
December 14, 2011
Treatment Development: The Past 50 Years
Dr. Insel discusses the state of psychiatric research and development (R&D) in the public and private sectors
December 06, 2011
Antidepressants: A complicated picture
Dr. Insel discusses the complicated nature of research on the efficacy antidepressants.
November 18, 2011
Neuroscience Advances Showcased in Washington
Dr. Insel reflects on an exciting neuroscience conference where an increasing interest in neuropsychiatric disorders was evident.
More Posts about Clinical Research and Trials
Meeting Summaries about Clinical Research and Trials
- Alliance for Research Progress — July 29, 2011 Meeting
- July 29, 2011
Bethesda, Maryland
Summary for the July 2011 meeting of the Alliance for Research Progress. - Alliance for Research Progress — February 18, 2011 Meeting
- February 18, 2011
Bethesda, Maryland
Summary for the February 2011 meeting of the Alliance for Research Progress. - Integrating Neuroscience, Developmental Psychopathology, and Preventive Interventions: Critical Questions for the Next Generation of Transformative Research
- June 01, 2010
Denver, Colorado
In conjunction with the 18th annual conference of the Society for Prevention Research, NIMH held a one-day, pre-conference workshop. The goal of the meeting was to identify strategies to advance prevention science research for mental disorders through the integration of basic science, neurodevelopment research, and intervention expertise. - Child and Adolescent Effectiveness Research in Clinical Practice and Community Settings: Needs, Challenges, and Opportunities
- January 24, 2008 – January 25, 2008
Washington, D.C.
This workshop provided a forum for reviewing accomplishments and challenges in conducting effectiveness research in practice and other community settings and served as an opportunity for informally discussing promising approaches to further research. The focus of the meeting was on testing the effectiveness of treatment interventions for children and adolescents when delivered in clinical practice and other community settings, such as schools. - Strategies for Developing Novel Interventions for Neurodevelopmental Disorders
- October 11, 2007
Bethesda, Maryland
The goal of this workshop was to explore novel treatment approaches to neurodevelopmental disorders and strategies for promoting the development of innovative therapeutic approaches.
More Meeting Summaries about Clinical Research and Trials
Director’s Updates about Clinical Research and Trials
- NIMH Perspective on Diagnosing and Treating Bipolar Disorder in Children
September 03, 2007
A recently published research paper (September 2007, Archives of General Psychiatry) reported a 40-fold increase in the rate of diagnosing bipolar disorder in youth over the past decade.
- NIMH Perspective on Antipsychotic Reimbursement: Using Results from the CATIE Cost Effectiveness Study
December 01, 2006
The recent publication (December 1, 2006, American Journal of Psychiatry) of the cost-effectiveness results from the National Institute of Mental Health (NIMH)-funded Clinical Antipsychotic Trials in Intervention Effectiveness (CATIE) has raised questions among advocates, families, and clinicians about reimbursement policies for antipsychotic medications.
- NIMH Perspective on Treating Alzheimer’s Patients with Antipsychotic Medications
October 12, 2006
The recent publication of phase 1 results from the NIMH-funded Clinical Antipsychotic Trials in Intervention Effectiveness for Alzheimer's disease (CATIE-AD) in the New England Journal of Medicine provides new information about the use of several "atypical" antipsychotic medications for the treatment of psychotic symptoms in patients with Alzheimer's disease.
NIMH Topics
Disorders
- Attention Deficit Hyperactivity Disorder (ADHD)
- Anxiety Disorders
- Autism
- Bipolar Disorder
- Borderline Personality Disorder
- Depression
- Eating Disorders
- Generalized Anxiety Disorder
- Obsessive-Compulsive Disorder (OCD)
- Panic Disorder
- Post-Traumatic Stress Disorder
- Schizophrenia
- Social Phobia
Populations
- Older Adults
- Men's Mental Health
- Military Servicemembers
- Women's Mental Health
- Children and Adolescents
