NIMH Pages about Schizophrenia
Learn more about Schizophrenia…
Clinical Trials Page
Find current studies on Schizophrenia…
Publications
- Schizophrenia
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A detailed booklet that describes symptoms, causes, and treatments, with information on getting help and coping.
Date: 2009
También disponible en Español - Schizophrenia (Easy-to-Read)
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An easy-to-read booklet on Schizophrenia that explains what it is, when it starts and how to get help.
Date: 2009 - Looking at My Genes: What Can They Tell Me?
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A fact sheet containing frequently asked questions about genome scans and genetic testing.
Date: 2008
Science News
- Mental Decline Thwarted in Aging Rats
- July 08, 2010 • Press Release
Scientists have discovered a compound that restores the capacity to form new memories in aging rats, likely by improving the survival of newborn neurons in the brain's memory hub. The research, funded in part by the National Institutes of Health, has turned up clues to a neuroprotective mechanism that could lead to a treatment for Alzheimer's disease. - Effectiveness of Long-term Use of Antipsychotic Medication to Treat Childhood Schizophrenia is Limited
- May 17, 2010 • Science Update
Few youths with early-onset schizophrenia who are treated with antipsychotic medications for up to a year appear to benefit from their initial treatment choice over the long term, according to results from an NIMH-funded study. The study was published online ahead of print May 4, 2010, in the Journal of the American Academy of Child and Adolescent Psychiatry. - Impaired Brain Connections Traced to Schizophrenia Mutation
- March 31, 2010 • Press Release
The strongest known recurrent genetic cause of schizophrenia impairs communications between the brain’s decision-making and memory hubs, resulting in working memory deficits, according to a study in mice. - Genes and Circuitry, Not Just Clinical Observation, to Guide Classification for Research
- January 28, 2010 • Science Update
NIMH is launching a long-term project aimed at ultimately improving treatment and prevention by studying classification of mental illness, based on genetics and neuroscience in addition to clinical observation. The Research Domain Criteria (RDoC) project is not intended to replace psychiatry’s existing diagnostic system for practitioners and will proceed in an independent direction, said Bruce Cuthbert, Ph.D., Director of the NIMH Division of Adult Translational Research, who is directing the effort. By taking a fresh look – without preconceived categories – the project aims to improve the validity of classification for researchers. - Symptoms in Mice Lacking a Single Receptor Type Mimic the Development of Schizophrenia
- December 03, 2009 • Science Update
Deleting one type of neurotransmitter receptor in a specific population of brain cells can induce schizophrenia-like behavior in mice, but only when the receptor is deleted early in development, according to a study by NIMH intramural scientists. The work provides strong support for previous observations implicating these receptors in psychosis; further, the mice provide a model of how psychotic symptoms can arise from a disruption in neuronal development, consistent with observations of how schizophrenia emerges in humans.
Meeting Summaries
- Child and Adolescent Onset Schizophrenia: Research Challenges and Opportunities
- June 25, 2007 – June 26, 2007
Bethesda, Maryland
In June 2007, NIMH and the NIH ORD convened a meeting for brainstorming and discussion between basic, translational, and clinical investigators to review the current knowledge on causes, neurobiology, developmental trajectory, and treatment of child- and adolescent-onset schizophrenia. - International Society for CNS Clinical Trials and Methodology (ISCTM) Meeting
- January 20, 2006
Washington, DC
In February 2006, the ISCTM held this meeting by satellite on the NIMH initiative regarding treatment development for negative symptoms of schizophrenia.
