Featured Studies
Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
- Effectiveness of a Behavioral Treatment Program for Attention Deficit Hyperactivity Disorder, Inattentive Type.
Interventional study. This study will test the effectiveness of a new behavioral treatment, called the Child Life and Attention Skills Program, for children with attention deficit hyperactivity disorder, inattentive type. Ages 7-11. Locations in Berkeley, CA; San Francisco, CA.
- Treatment of Severe Childhood Aggression (The TOSCA Study).
Interventional study. This study will determine the safety and effectiveness of two medications for treating aggression in children with attention deficit hyperactivity disorder (ADHD). Ages 6-12. Locations in Stony Brook, NY; Cleveland, OH; Columbus, OH; Pittsburgh, PA.
- Effectiveness of Combined Medication Treatment for Aggression in Children With Attention Deficit With Hyperactivity Disorder (The SPICY Study).
Interventional study. This study will determine the advantages and disadvantages of adding one of two different types of drugs to stimulant treatment for reducing aggressive behavior in children with attention deficit with hyperactivity disorder (ADHD). Ages 6-12. Locations in Glen Oaks, NY; Stony Brook, NY; San Antonio, TX.
- A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation.
Interventional study. Severe mood dysregulation (SMD) is a very common syndrome in children. Ages 7-17. Location in Bethesda, MD.
- Atomoxetine and Parent Management Training in Treating Children With Autism and Symptoms of Attention Deficit Disorder With Hyperactivity.
Interventional study. This study will evaluate the effectiveness of the medication atomoxetine, with and without parent management training, in treating children with autism or pervasive developmental disorder not otherwise specified who have symptoms of attention deficit hyperactivity disorder. Ages 5-14. Locations in Rochester, NY; Columbus, OH; Pittsburgh, PA.
- Group-Based Behavioral Therapy Combined With Stimulant Medication for Treating Children With Attention Deficit Hyperactivity Disorder and Impaired Mood.
Interventional study. This study will evaluate the effectiveness of an integrative group psychosocial therapy combined with stimulant medication in treating children with attention deficit hyperactivity disorder plus impairments in mood. Ages 7-11. Location in Buffalo, NY.
- Effectiveness of School- and Home-Based Mental Health Services in Improving Learning and Behavior in Children in Urban Schools.
Interventional study. This study will evaluate the effectiveness of school- and home-based mental health services and training modules in supporting learning and behavior in financially disadvantaged children who live in urban areas. Ages 5-12. Location in Chicago, IL.
- Effectiveness of Collaborative Services in Primary Care for Treating Children With Behavior Disorders.
Interventional study. This study will evaluate the effectiveness of a doctor-office collaborative care approach in treating children with disruptive behavior problems in the pediatric primary care setting. Ages 5-12. Location in Pittsburgh, PA.
- Single Versus Combination Medication Treatment for Children With Attention Deficit Hyperactivity Disorder.
Interventional study. This study will evaluate the effectiveness of a single drug versus a combination of drugs in treating attention deficit hyperactivity disorder in children. Ages 7-14. Location in Los Angeles, CA.
- Parent Training to Promote Early Identification and Treatment of Childhood Behavioral Disorders.
Interventional study. This study will evaluate the effectiveness of a parent training program in improving parenting skills and reducing behavioral symptoms in young children who are at risk for developing childhood behavior disorders. Ages 22 months-38 months. Locations in Chelsea, MA; Dorchester, MA; Leominster, MA; Westford, MA; Westwood, MA; Woburn, MA.
- Organizational Skills Training for Children With Attention Deficit Hyperactivity Disorder.
Interventional study. This study will evaluate the effectiveness of organizational skills training in improving organizational, time management, and planning difficulties in children with attention deficit hyperactivity disorder. Ages 8-11. Locations in New York, NY; Durham, NC.
- Stimulant Versus Nonstimulant Medication for Attention Deficit Hyperactivity Disorder in Children.
Interventional study. This study will determine the effectiveness of stimulant and nonstimulant medication in treating the symptoms of attention deficit hyperactivity disorder (ADHD) in children and adolescents. Ages 6-17. Locations in Chicago, IL; New York City, NY.
- Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children.
Interventional study. This study will first examine the cognitive and behavioral differences in children who have an autism spectrum disorder (ASD) and who do and do not have additional symptoms of attention deficit hyperactivity disorder (ADHD). Ages 7-12. Location in Houston, TX.
- Improving Attention Deficit Hyperactivity Disorder Treatment Adherence and Outcome in Primary Care Settings.
Interventional study. This study will determine the effectiveness of educating pediatricians about attention deficit hyperactivity disorder treatment guidelines in improving child behavior and pediatricians' adherence to medication guidelines. Ages 6-11. Location in Chicago, IL.
- A Clinic-Based Prevention Program for Families of Depressed Mothers.
Interventional study. This study will assess the effectiveness of the "Keeping Families Strong" program (KFS) in avoiding or delaying the onset of psychiatric disorders among children with depressed mothers. Ages 8 and over. Location in Baltimore, MD.
- Brain Changes in Children and Adolescents With Behavioral Problems.
Evaluation study. Purpose: This study will examine brain activity in children age 10-18 with disruptive behavior problems, including conduct disorder (CD), oppositional defiant disorder (ODD), and attention deficit hyperactivity disorder (ADHD), compared with children without behavioral problems. Ages 8-18. Location in Bethesda, MD.
Related Information
- Learn more about Attention Deficit Hyperactivity Disorder (ADHD, ADD)
Attention Deficit Hyperactivity Disorder, ADHD, is one of the most common mental disorders that develop in children. Children with ADHD have impaired functioning in multiple settings, including home, school, and in relationships with peers. If untreated, the disorder can have long-term adverse effects into adolescence and adulthood.
Clinical Research at NIMH
- For opportunities to participate in NIMH research on the NIH campus, visit the patient recruitment Website. Travel and lodging assistance available.
