Featured Studies
Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
- Alprazolam and Eating Behavior in Anorexia Nervosa.
Evaluation study. This study examines the role of anxiety in food intake among patients with AN by measuring caloric intake in a standardized, laboratory meal with alprazolam versus a placebo. Ages 16-55. Location in New York, NY.
- Olanzapine Versus Placebo for Outpatients With Anorexia Nervosa.
Interventional study. Anorexia Nervosa (AN) is a serious illness associated with substantial morbidity and mortality. Ages 18-55. Locations in Baltimore, MD; New York, NY; White Plains, NY; Pittsburgh, PA; Toronto, Canada.
- Characteristics and Importance of Physical Activity in Women With Anorexia Nervosa.
Evaluation study. This study will determine the importance and the level of physical activity among women with anorexia nervosa, both during inpatient treatment and 1 year after hospital discharge. Ages 16-40. Location in New York, NY.
- Testing an Alternative Therapy for Bulimia Nervosa.
Interventional study. This study will compare a new method of treatment for bulimia nervosa (ICAT), integrative cognitive-affective therapy, to the current standard method of treatment, cognitive behavioral therapy (CBT). Ages 18-65. Locations in Minneapolis, MN; Fargo, ND.
- Changes in Dopamine Levels Before and After Weight Restoration in People With Anorexia Nervosa.
Evaluation study. This study will use positron emission tomography imaging to investigate changes in dopamine systems in people with anorexia nervosa before and after weight restoration. Ages 18-45. Location in New York, NY.
- Pharmacogenomics of Antidepressant Response in Children and Adolescents.
Evaluation study. This study will identify variations in genes that may be involved in the development of suicidal events or certain behaviors in youth who are exposed to antidepressant medications. Ages 7-17. Location in Durham, NC.
- Focused Versus Enhanced Cognitive Behavioral Therapy for Treating Women With Bulimia Nervosa.
Interventional study. This study will compare the effectiveness of two types of cognitive behavioral therapy in treating adult women with the dysregulated subtype of bulimia nervosa. Ages 18-65. Location in Boston, MA.
- An fMRI Study of Self-regulation in Adolescents With Bulimia Nervosa.
Evaluation study. The aim of this project is to use both functional MRI (fMRI) and behavioral measures to investigate how disturbances in frontostriatal neural systems contribute to the impulsive and habitual binge-eating behaviors in patients with Bulimia Nervosa (BN). Ages 12-21. Location in New York, NY.
- Serotonin Transporter Concentrations in Women With a History of Anorexia Nervosa.
Evaluation study. This study will compare the concentrations of serotonin transporter in the brains of women with a history of anorexia nervosa who are currently maintaining a normal weight to those of healthy women of normal weight. Ages 18-45. Location in New York, NY.
Search ClinicalTrials.gov for other NIH studies on Eating Disorders.
Related Information
- Learn more about Eating Disorders
Eating is controlled by many factors, including appetite, food availability, family, peer, and cultural practices, and attempts at voluntary control. Dieting to a body weight leaner than needed for health is highly promoted by current fashion trends, sales campaigns for special foods, and in some activities and professions.
Clinical Research at NIMH
- For opportunities to participate in NIMH research on the NIH campus, visit the patient recruitment Website. Travel and lodging assistance available.
