Featured Studies
Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
- Community-based Accompaniment With Supervised Antiretrovirals in Lima, Peru.
Interventional study. Using quantitative and qualitative data, this study will assess the impact of community accompaniment with supervised antiretrovirals (CASA) on HIV-positive individuals and community members in Lima, Peru. Ages 18 and over. Location in Lima, Peru.
- Telephone Based Cognitive Behavioral Therapy for HIV Related Depression.
Interventional study. The purpose of this study is to evaluate the effectiveness of a telephone-based, cognitive behavioral therapy intervention in the treatment of depression in adults diagnosed with HIV. Ages 18 and over. Location in Baltimore, MD.
- Testing an HIV Prevention Intervention for Psychiatric Patients in Brazil.
Interventional study. This study will test the effectiveness of a program aimed at reducing behaviors that increase HIV risk among people with severe mental illnesses. Ages 18-80. Location in Rio de Janeiro, Brazil.
- Determining Characteristics and Behaviors of Adolescent Women Regarding HIV Risk and Microbicide Trial Participation.
Evaluation study. This study will examine characteristics and behaviors of young women in India and Tanzania to determine which challenges and opportunities exist for conducting future trials of HIV prevention treatments. Ages 15-21. Location in Dar es Salaam, Tanzania.
- The Use of a Distress Thermometer in a Pediatric Research Setting: An Exploratory Pilot Study.
Evaluation study. Medical illnesses and treatments can cause distress in patients, and medical professionals are very interested in identifying distress quickly to ensure that a patient can receive appropriate support and treatment. Ages 7-21. Location in Bethesda, MD.
- Brain Deficits in HIV/HCV Coinfected People Before and After Anti-HCV Therapy.
Evaluation study. This study will evaluate the impact of standard hepatitis C virus treatment on brain deficits in people who are infected with both HIV and the hepatitis C virus. Ages 18 and over. Locations in Lancaster, CA; Los Angeles, CA.
- A School-Based HIV/STD Prevention Program to Reduce Risky Sexual Behaviors Among Adolescents in Liberia.
Interventional study. This study will evaluate the effectiveness of a school-based HIV/sexually transmitted disease prevention program in reducing sexual risk behaviors of youth attending school in Liberia. Ages 13-15. Location in Monrovia, Liberia.
- Effectiveness of Community-Level Behavioral and Biomedical Interventions for Reducing HIV/STIs in Men in Peru.
Interventional study. This study will evaluate the effectiveness of community-level behavioral and biomedical interventions, each alone and combined, in reducing sexual risk behavior and HIV/sexually transmitted infections in Peruvian men who have sex with men. Ages 18-45. Location in Lima, Peru.
- Providing Voluntary HIV Counseling and Testing Plus Linkage to Care in Uganda.
Interventional study. This study will compare the effectiveness of brief versus detailed HIV counseling sessions, paired with referrals to either HIV-specific medical care or usual care, in reducing HIV risk behavior and in increasing treatment adherence in Uganda. Ages 18 and over. Location in Kampala, Uganda.
- Effectiveness of HIV/Sexually Transmitted Infection Training for Physicians in China.
Interventional study. This study will evaluate the effectiveness of a physician training program, the Ai Shi Zi program, in improving HIV/sexually transmitted infection diagnosis, treatment, and management by Chinese physicians and in reducing the number of subsequent infections in their patients. Ages 18-45. Location in Hefei, China.
- Effectiveness of Integrating Prenatal Care in Reducing HIV/STDs Among Young Pregnant Women.
Interventional study. This study will evaluate the effectiveness of CenteringPregnancy Plus, a group prenatal care treatment program with an HIV/sexually transmitted disease prevention component, in reducing health risk behaviors in pregnant teenagers seeking services at Community Health Centers in the New York metropolitan area. Ages 14-21. Locations in Cheshire, CT; New Haven, CT; New York, NY.
- Cognitive Behavioral Therapy to Help HIV Infected Adults With Depression to Adhere to Antiretroviral Therapy.
Interventional study. This study will compare the effectiveness of a cognitive behavioral intervention versus usual clinic care in helping HIV infected adults with depression to take their HIV medications on schedule. Ages 18-60. Location in Torrance, CA.
- Effects of HIV and Hepatitis C Virus on the Brain.
Evaluation study. This study will determine the effects that HIV and hepatitis C virus have on thinking abilities and whether the viruses affect brain chemistry. Ages 18-65. Location in New York, NY.
- PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD).
Interventional study. The purpose of this protocol is to measure a receptor in the brain using positron emission tomography (PET) that is involved in inflammation. Ages 18-50. Locations in Baltimore, MD; Bethesda, MD.
- Effectiveness of a Telephone-Delivered Behavioral Treatment to Improve the Quality of Life of Older Adults With HIV.
Interventional study. This study will evaluate the effectiveness of a telephone-delivered coping improvement group intervention in improving quality of life in older adults with HIV. Ages 50 and over. Location in Athens, OH.
- STD Risk Reduction for Heterosexual Methamphetamine Users.
Interventional study. This study will evaluate the effectiveness of a sexual risk reduction intervention in reducing sexual risk behavior in HIV uninfected, heterosexual people who use methamphetamine. Ages 18 and over. Location in San Diego, CA.
- Effectiveness of Structured Ecosystems Therapy for Reducing HIV Risk Behaviors and Improving Treatment Adherence in HIV Infected Men Released From Prison.
Interventional study. This study will evaluate the effectiveness of Structured Ecosystems Therapy (SET), a form of therapy that includes family and caregivers, at reducing HIV transmission risk behaviors and improving treatment adherence in HIV infected men newly released from prison. Ages 18 and over. Location in San Francisco, CA.
- Antidepressant Medication Plus Directly Observed Therapy for Improving Adherence to Antiretroviral Therapy.
Interventional study. This study will evaluate the effectiveness of directly observed therapy plus antidepressant medication in improving adherence to antiretroviral drug therapy among HIV-infected homeless and marginally housed people with depression. Ages 18 and over. Location in San Francisco, CA.
- Modified Directly Observed Therapy for Improving Antiretroviral Therapy Adherence in People With HIV.
Interventional study. This study will evaluate the effectiveness of a modified directly observed therapy program in increasing antiretroviral therapy adherence in poor, HIV-infected residents of urban communities. Ages 18 and over. Location in San Francisco, CA.
- Specialized Cognitive-Behavioral Counseling Intervention to Reduce HIV Transmission Risk Behavior in HIV-Infected Men.
Interventional study. This study will evaluate the effectiveness of a specialized cognitive-behavioral counseling intervention in reducing sexual risk behaviors in men who are HIV-infected and report having unprotected sex with male partners who are either not HIV-infected or do not know if they are HIV-infected. Ages 18 and over. Location in San Francisco, CA.
- Community Mobilization, Mobile Testing, Same-Day Results, and Post-Test Support for HIV in Sub-Saharan Africa and Thailand.
Interventional study. This study will evaluate the effectiveness of a combination of clinic- and community-based voluntary counseling and testing programs in preventing HIV in African and Thai communities. Ages 16 and over. Locations in Soweto, Johannesburg, South Africa; Pietermaritzburg, South Africa; Dar es Salaam, Tanzania; Chiang Mai, Thailand; Harare, Zimbabwe.
- Managed Problem Solving to Increase Treatment Adherence in Individuals With HIV.
Interventional study. This study will determine whether a managed problem solving intervention can help patients with HIV better follow their anti-HIV drug regimen and can control HIV better than the standard of care. Ages 18 and over. Location in Philadelphia, PA.
Search ClinicalTrials.gov for other NIH studies on HIV/AIDS.
Related Information
Clinical Research at NIMH
- For opportunities to participate in NIMH research on the NIH campus, visit the patient recruitment Website. Travel and lodging assistance available.
