Featured Studies
Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
- Teens Coping With Parental Military Deployment.
Interventional study. The total number of military personnel is over 3.5 million and approximately 43% have children. Ages 13-17. Location in Providence, RI.
- Examining the Effectiveness of an Early Psychological Intervention to Prevent Post-Traumatic Stress Disorder.
Interventional study. This study will examine the use of prolonged exposure therapy on people who have recently experienced a trauma to prevent them from developing post-traumatic stress disorder. Ages 18-65. Location in Atlanta, GA.
- Effectiveness of a Web-Based Intervention for Guardians of Children Whose One Parent Has Murdered the Other.
Interventional study. This study will determine whether a specialized Web site geared for the guardians of children whose one parent has murdered the other can increase guardian capabilities, reduce guardian stress, and improve child behavior and mental health. Ages 18 and over. Location in Charlottesville, VA.
- Effectiveness of Cognitive Behavioral Couples Therapy for Post-traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of cognitive behavioral couples therapy designed for post-traumatic stress disorder in reducing symptoms of post-traumatic stress disorder and in improving relationship functioning. Ages 18-75. Location in Toronto, Canada.
- Effectiveness of Propranolol For Treating People With Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of propranolol in reducing symptoms of distress in people with post-traumatic stress disorder. Ages 18-50. Location in New York, NY.
- Evaluating the Effects of Stress in Pregnancy.
Evaluation study. This study will evaluate pregnant women with a past or current diagnosis of depression or anxiety to gain a better understanding of how these disorders can affect an infant's development, both during and after pregnancy. Ages 18-45. Location in Atlanta, GA.
- Cognitive Behavioral Treatment for Post-Traumatic Stress Disorder in People With Additional Serious Mental Illnesses.
Interventional study. This study will evaluate the effectiveness of tailored cognitive behavioral therapy in treating post-traumatic stress disorder in people with additional mental illnesses. Ages 18 and over. Locations in Monmouth Junction, NJ; New Brunswick, NJ; Newark, NJ.
- Comparing Behavioral Therapies for Treating Adolescents With Post-Traumatic Stress Disorder Related to Sexual Abuse.
Interventional study. This study will evaluate the comparative effectiveness of prolonged exposure therapy and client centered therapy in treating adolescents with post-traumatic stress disorder related to childhood sexual abuse or assault. Ages 13-18. Location in Philadelphia, PA.
- Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders.
Evaluation study. This study is intended to help develop new MRI imaging techniques for studying mood and anxiety disorders. Ages 18-50. Location in Bethesda, MD.
- Effectiveness of Virtual Reality Exposure Therapy and D-Cycloserine to Treat Iraq War Veterans With Post-Traumatic Stress Disorder.
Interventional study. This study will determine whether a combination of virtual reality exposure therapy and D-cycloserine will reduce post-traumatic stress disorder symptoms in Iraq war veterans. Ages 21-65. Location in Atlanta, GA.
- Group Intervention for Interpersonal Trauma.
Interventional study. This study will assess the acceptability and effectiveness of a six-session, modular, repeating group for low-income women who have symptoms of depression and/or post-traumatic stress disorder following interpersonal trauma exposure. Ages 18-70. Location in Washington, DC.
- Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of prazosin in treating post-traumatic stress disorder caused by noncombat trauma in individuals taking selective serotonin reuptake inhibitors. Ages 18 and over. Location in Seattle, WA.
- Psychobiological Mechanisms of Resilience to Trauma.
Evaluation study. This study will evaluate brain changes and psychological characteristics of people who are resilient to trauma. Ages 18 and over. Locations in Washington, DC; Bethesda, MD.
Search ClinicalTrials.gov for other NIH studies on Post-Traumatic Stress Disorder (PTSD).
Related Information
- Learn more about Post-Traumatic Stress Disorder (PTSD)
Post-Traumatic Stress Disorder (PTSD is an anxiety disorder that can develop after exposure to a terrifying event or ordeal in which grave physical harm occurred or was threatened. Traumatic events that may trigger PTSD include violent personal assaults, natural or human-caused disasters, accidents, or military combat.
Clinical Research at NIMH
- For opportunities to participate in NIMH research on the NIH campus, visit the patient recruitment Website. Travel and lodging assistance available.
